Risk Factors of Deep Venous Thrombosis in Duplex and Colour Doppler Ultrasound at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

Abstract

Background: Deep venous thrombosis is a major health problem with high morbidity and mortality worldwide. Thus early, correct and definitive diagnosis is crucial in assessing thromboembolic risk and initiating therapy. In this regard Patients at risk must be identified and given appropriate prophylaxis to reduce Venous Thromboembolism related morbidity and mortality.The main objective of this study was to determine common risk factors of deep venous thrombosis (DVT) and the common sites involved by DVT in ultrasound proven cases.

Methods: This was a prospective cross-sectional study which included all patients who had proven deep venous thrombosis by Dopper and duplex ultrasound at Tikur Anbessa Specialized Hospital (TASH). Senior radiology residents collected the data after getting approval from consultant radiologists. Analysis was under taken by principal investigator.

Results: There were a total 81 ultrasound proven cases of DVT involving the extremities during the study period out of which 34.6% were males and 65.4% females. The majority (58%) were under the age of 40 years. Malignancy was the most common identified risk factor (30.9% of the cases) followed by prolonged immobilization 19.8%, pregnancy related problems 6.2% and severe trauma 6.2% of the patients. No apparent risk factor was found in 12.3%. Swelling was noted in 93.8% of the participants in combination with other manifestations or alone; whereas pain was noted in 70.4% of the patients. The study showed 59.3% had involvement of the left lower limb only; 11.1% had involvement of both lower limbs. The upper extremities were affected in only one patient having bilateral involvement of brachiocephalic veins. According to the study 84% of the patients had combined involvement of the deep veins of the lower extremities extending from the common iliac veins to the poplitial veins. The study revealed that 28.4% of participants were found to havecombined involvement of the common femoral vein (CFV), superficial femoral vein (SFV) & poplitial vein; 22.2% had combined involvement of the CFV & SFV.

Conclusion: From the study we concluded that Malignancy, prolonged immobilization, pregnancy related problems and major trauma were the most common risk factors noted for DVT and Swelling was the most common presenting manifestation. Majority of the patients had multiple site deep vein involvement extending from the common iliac to the poplitial veins.

Key words: Risk, Factors, Deep, Vein, Thrombosis, Duplex,Doppler.