Prevalence and Severity of Adverse Drug Reactions among Adult Patients Using Antiretroviral New Default and Modified Default First Line Regimens in Mbeya Region, Tanzania

Abstract

A comparative study of the prevalence of adverse drug reactions due to zidovudine/lamivudine/efavirenz (new default first line) and zidovudine/lamivudine/nevirapine (modified default first line) regimens was done in Mbeya Region, Tanzania. The new default first line regimen was found to be safer than the modified default first line regimen. This study provides antiretrovirals safety profiles and potential information for patient health  management planning and decision making.

Key words: Antiretroviral regimens, adverse drug reactions, prevalence