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Phytosterols from Dombeya torrida (J. F. Gmel.)


SN Ndwigah
GN Thoithi
JW Mwangi
BK Amugune
HN Mugo
IO Kibwage

Abstract

Dombeya torrida collected from Kinale forest in Kiambu County, Kenya, was Soxhlet extracted with chloroform and by percolation using a  dichloromethane:methanol mixture. The extracts were fractionated using normal phase silica gel in an open column. Five compounds were isolated namely friedelin, friedelan-3β-ol, α-sitosterol, taraxerol and stigmasterol. This is the first report of isolation of these compounds from Dombeya torrida. The isolated compounds were identified by means of 1H-NMR, 13C-NMR, DEPT, MS and IR analyses.

Key words: Dombeya torrida, friedelin, friedelan-3β-ol, β-sitosterol, stigmasterol, taraxerol.


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eISSN: 1026-552X