Assessment of Biochemical Parameters of Graft Survivors Post Renal Transplantation at King Faisal Hospital in Rwanda

Abstract

Background: Chronic kidney disease (CKD) remains a public health concern of 21st century. Each year, over million people die from CKD resulting from the lack of proper diagnosis and treatment of this terrible disease of the urinary system. Non-communicable diseases (NCDs) cause roughly 60% of all deaths worldwide. There is insufficient data in Rwanda for the management of kidney diseases and other NCDs for all health facilities. Renal substitution therapy appears to be the best solution for long–suffering patients with end-stage renal illness who want to survive. The study’s purpose was to find out the serum creatinine and blood urea nitrogen (BUN) concentrations among kidney transplanted patients at King Faisal Hospital of Rwanda, and to show the consequences linked with the transplantation of kidney.
Methods: This was a retrospective study carried from November 2018 to December 2019. The data were collected from medical records at King Faisal Referral Hospital, and analysed with SPSS version 22.
Results: BUN and serum creatinine concentrations ranged from 77.4 to 93.5% and 67.8 to 87.1%, respectively. BUN levels that were abnormally high ranged from 3.2 to 19.4%, while creatinine levels that were abnormally high ranged from 6.5 to 29.0%. BUN and creatinine levels that were abnormally low, ranged from 0.0 to 6.5 and 3.2 to 9.7%, respectively. Diabetes mellitus affected 19.35% of the study population, hypertension affected 35.48%, and antibodymediated rejection affected 6.45%.
Conclusion: The slight change in biochemical parameters may be a problem after kidney transplantation. There should be a monitoring of biochemical parameters tests to prevent the post kidney transplantation complications.