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Effect of Helicobacter pylori infection on deep vein thrombosis seen in patients with Behçet's disease
Abstract
Objective: To investigate the role of homocysteine metabolism due to Helicobacter pylori infection on the development of deep vein thrombosis (DVT) in patients with Behcet's disease (BD).
Design: Prospective clinical study.
Setting: Teaching hospital.
Subject: Fifty-five patients with BD divided into groups, with DVT and without DVT, 19 healthy individuals and 18 patients with coronary artery disease (CAD) were enrolled into the study.
Interventions: Plasma homocysteine and Hp seropositivity were determined.
Results: There was significant Hp positivity in all groups (p>0.05). Homocysteine levels were not significantly different for each group except patients with CAD (p>0.05).
Conclusion: There was no difference for frequency of Hp infection in all groups. We conclude that Hp does not influence DVT seen in BD via homocysteine metabolism, but the methinnin-loading test would be appropriate for enlighting patients whose fasting plasma homocysteine levels are found to be normal.
East African Medical Journal Vol. 83(1) 2006: 49-51
Design: Prospective clinical study.
Setting: Teaching hospital.
Subject: Fifty-five patients with BD divided into groups, with DVT and without DVT, 19 healthy individuals and 18 patients with coronary artery disease (CAD) were enrolled into the study.
Interventions: Plasma homocysteine and Hp seropositivity were determined.
Results: There was significant Hp positivity in all groups (p>0.05). Homocysteine levels were not significantly different for each group except patients with CAD (p>0.05).
Conclusion: There was no difference for frequency of Hp infection in all groups. We conclude that Hp does not influence DVT seen in BD via homocysteine metabolism, but the methinnin-loading test would be appropriate for enlighting patients whose fasting plasma homocysteine levels are found to be normal.
East African Medical Journal Vol. 83(1) 2006: 49-51
