Main Article Content
DNA Genotype of Human Papilloma Virus Infection among Adolescent Girls at Kenyatta National Hospital Youth Clinic
Abstract
Background: Adolescents have risky sexual behaviour exposing them to the Human Papilloma Virus (HPV ) infection. With clear causal relationship between high risk the HPV (16 and 18) infection and invasive cancer, this study focuses on the distribution of HPV genotypes among the female adolescent and youth at the Kenyatta National Hospital (KNH) youth clinic.
Objective: To determine DNA genotype of HPV infection among adolescent girls at KNH - Youth Clinic and use it as an advocacy tool for the introduction of the HPV vaccine provision in the clinic.
Design: Cross-sectional study.
Setting: Kenyatta National Hospital Youth clinic.
Subjects: Adolescent (and youths) girls aged between 12-24 years.
Results: Two hundred and sixty four participants were recruited into the study for a period of three months. The recruitment was done in the clinic till the required sample size was obtained. The prevalence of cervical HPV infection was 9.8% (95% CI : 6.13 to 13.41). There were multiple serotypes with 27% infected with HPV strain type 18 and 66. Type 16 was 5%, type 18 was 9%, and there were mixed genotype infections in the rest. There were no low risk strains isolated and 18% of the respondents who tested positive for HPV DNA had uncharacterised strains.
Conclusion: The prevalence of HPV among the adolescent girls at KNH youth clinic was 9.8%. Twenty seven percent had co-infection with type 18 and 66.
Objective: To determine DNA genotype of HPV infection among adolescent girls at KNH - Youth Clinic and use it as an advocacy tool for the introduction of the HPV vaccine provision in the clinic.
Design: Cross-sectional study.
Setting: Kenyatta National Hospital Youth clinic.
Subjects: Adolescent (and youths) girls aged between 12-24 years.
Results: Two hundred and sixty four participants were recruited into the study for a period of three months. The recruitment was done in the clinic till the required sample size was obtained. The prevalence of cervical HPV infection was 9.8% (95% CI : 6.13 to 13.41). There were multiple serotypes with 27% infected with HPV strain type 18 and 66. Type 16 was 5%, type 18 was 9%, and there were mixed genotype infections in the rest. There were no low risk strains isolated and 18% of the respondents who tested positive for HPV DNA had uncharacterised strains.
Conclusion: The prevalence of HPV among the adolescent girls at KNH youth clinic was 9.8%. Twenty seven percent had co-infection with type 18 and 66.
