Correlates of missed visits by participants enrolled in a HIV prevention clinical trial in Eldoret, Kenya

Abstract

Objectives: To identify the factors associated with missing at least one visit among participants enrolled in the HSV/HIV Transmission  Study, Eldoret Site.

Design: This was a retrospective study. Descriptive statistics for categorical and continuous variables were used to summarize data.  Association between categorical variables was assessed using Pearson’s Chi-square test. Continuous variables were compared using two- sample Wilcoxon rank sum test. The relationship between the binary outcome and independent variables was assessed using logistic  regression model. We reported the adjusted odds ratios (AOR) alongside the 95% confidence intervals.

Setting: The records of the participants enrolled in the Partners HSV/HIV Transmission Study, Eldoret Site formed the study population  for this study.

Results: The median number of missed visits was 2 (IQR: 1-4). More female participants missed at least a visit (45% vs  34%). Fifty-seven percent of participants who reported social harm missed at least a visit. HIV status and distance > 100km to the clinic  were associated with increased odds of missing at least 1 visit; AOR: 7.40 (95% CI: 3.95, 13.84); AOR: 4.49 (95% CI: 2.07, 9.73) respectively.  A participant from a family with one additional child compared to another was associated with reduced odds of missing at least 1 visit,  AOR: 0.84 (95% CI: 0.73, 0.96).

Conclusion: HIV status, distance of more than 100 kilometers and number of children were associated with  missing at least one visit among individuals in HIV-1 sero-discordant relationships participating in the HIV prevention clinical trial in  Eldoret.