Effects of rumenotomy plus infusion of two saline crystalloid solutions on serum biochemical parameters and erythrocye osmotic fragility of West African Dwarf Goats

Abstract

Objectives: Fifteen West African dwarf (WAD) goats were randomly assigned to three experimental groups to study the effects of  dextrose saline (DS) and normal saline (NS) infusions solutions on serum biochemical parameters and erythrocyte osmotic fragility of rumenotomized goats.
Design: Post rumenotomy, goats in groups 1 and 2 were administered with NS and DS while group 3 goats received no fluid. Serum concentrations of total plasma protein (TPP), blood urea nitrogen (BUN), chloride, sodium, potassium, calcium and bicarbonate were subsequently assayed. Body weights, blood glucose and erythrocyte osmotic fragility were determined
Results: On day 1 post rumenotomy (PSRT), mean TPP concentration of group 1 was significantly (P<0.05) higher than that of groups 2 and 3 whereas mean BUN concentrations of groups 1 and 3 were significantly (P<0.05) higher than BUN of group 2. Mean body weight of group 3 was significantly (P<0.05) lower than those of groups 1 and 2 throughout the study. Mean glucose concentration of group 3 was significantly (P<0.05) highest on days 1, 3 and 7 PSRT. Mean sodium concentrations of groups 1 and 2 were significantly (P<0.05) higher than those of group 3 on day 1 PSRT. The osmotic effect of normal saline was significantly (P<0.05) more than that of dextrose saline on PSRT days 2 and 3.
Conclusion: The outcome of this study showed that fluid infusion ameliorated the biochemical changes PSRT. However, normal saline exerted more osmotic effect on erythrocytes of goats.