Lipidemia status among HIV positive adult male on HAART attending the HIV clinic at Kericho district hospital, Kericho

Abstract

Background: It is unfortunate that while Highly Active Anti-retroviral Therapy (HAART) has become the standard of care among HIV positive patients, the medications have been associated with metabolic abnormalities recognised to cause lipidemia.

Objective: To establish lipidemia status among HIV positive adult male patients attending HIV clinic at Kericho District Hospital.

Design: A cross sectional analytical study.

Setting: HIV clinic at Kericho District Hospital, Kenya.

Subjects: HIV positive adult male patients

Results: The results indicated that the mean age was 43.52 ± 9.17 years and out of which 82.27% were married. Primary Education level attained 40.97% .The mean lipid profile level was LDL 2.5 ± 1.05mmol/l, cholesterol 4.49 mmol/L ± 1.28 mmol/l, HDL 1.47 ± 0.58 mmol/l and triglycerides 1.96 ± 1.32 mmol/l, against the expected level of LDL (1.1. - 2.4 mmol/L), HDL (0.9 - 1.68 mmol/L) triglyceride (0.41 - 2.61 mmol/L) and total cholesterol (2.55 - 5.7 mmol/L).The prevalence lipidemia was 48.17%.

Conclusion: The findings showed that the mean LDL was elevated with proportion of lipidemia at a significant higher level among HIV positive adult patients on HAART with considerable improvement in the nutritional status. Future work should investigate the biological mechanisms and pathways through which micronutrients affects high density lipoprotein (HDL) and low density lipoproteins (LDL).