Elemental Profile in Amniotic Fluid of some Nigerian Pregnant Women

Abstract

In this study concentration level of calcium, cadmium, copper, iron, magnesium, manganese, nickel, lead and zinc were determined in the amniotic fluid of pregnant women, aged 15 – 45 years enrolled at the Obafemi Awolowo University Teaching Hospitals Complex Ile – Ife. This was with a view to predict the body burden of the metals in the pregnant women and assess the health implications of the toxic elements to the pregnant
women and their fetuses. Fifty samples of the amniotic fluid were collected from the pregnant women. The efficiency of extraction of trace metals  using conventional wet acid digestion method (CDM) and microwave induced acid digestion method (MWD) was determined by recovery  experiments. Levels of trace metals were determined using Atomic  Absorption Spectrophotometry. The high percentage recoveries obtained  from MWD made it a more efficient method than the CDM and hence its adoption for sample digestion. Statistical analysis of data using descriptive and inferential statistics revealed that age; education and profession have effects on the levels of the trace metals. The mean levels of most of the toxic metals obtained in this study were lower than the recommended limits of trace metals in women whole blood.

Key Words: Amniotic Fluid, Pregnant Women, Metals, Nigeria