ATR-FTIR and GC-MS Analysis of Potentially Bioactive Compounds From Bridelia ferruginea Bark, Khaya senegalensis Bark and Psidium guajava Leaves

Abstract

Plants are of therapeutic value due to their diverse phytochemicals that confer numerous pharmacological benefits. Bridelia ferruginea,  Khaya senegalensis, and Psidium guajava, contain bioactive components with potential therapeutic applications, particularly in treating  gastrointestinal diseases. To investigate their chemical composition, the bark of Brideliaferruginea, Khaya senegalensis bark, and Psidium  guajava leaves were analyzed using Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR), and Gas  Chromatography-Mass Spectrometry (GC-MS). The functional groups and chemical compositions were identified and quantified using  advanced spectrometers from Agilent Technologies. The GC-MS analysis revealed distinct phytochemical profiles for each plant, with 18  compounds detected in B. ferruginea, 11 in K. senegalensis, and 32 in P. guajava. Attenuated Total Reflectance-Fourier Transform  Infrared (ATR-FTIR) analysis confirmed the presence of phenols, alcohols, aromatic compounds, esters, ethers in all three plants. These  findings suggest that the bioactive compounds in these plant extracts may contribute to their pharmacological activities, particularly in  the treatment of gastrointestinal diseases.