Impact of administering leaf and bark extracts of some botanicals on body weight, PVC and RBC in Oryclagus cuniculus

Abstract

Humanity faces with many infections, including viral, bacterial, and fungal. Medical experts propose that individuals with strong immunity are more likely to survive infections compared to those with weaker immunity. Therefore, people should enhance their immunity through increased intake of fruits and vegetable sorme dictations with immune boosting properties to better withstand unforeseen infections. Cocktail of some herbal extracts which contained leaves of Sorghum biclor, Persea americana, Treculia africana and barks of Deteruim microcarpum were examined for boosting of pack cell volume (PCV) and red blood cell (RBC) of laboratory animals. It was done by feeding the cold extracts of the cocktail to groups of rabbits for 28 days (4weeks) at varied doses. PCV and RBC tests were subsequently carried out on the rabbits to determine the effects of the cocktail on the blood of the rabbits as well as body weights. The results revealed a steady increase in weights for the control rabbits which ranged between 23.69± 2.97 to 26.91± 4.32, PCV ranged between 32.7 to 36.9 and RBC ranged between 4.4x106 to 5.4 x106 while the treated rabbits experienced slight decreases in their body weights towards the end of the experiment, groups 1, 2 and 3 ranged between 21.73 ± 0.83 to 25.97 ± 3.73, 19.50 ± 1.05 to 24.69 ± 4.82 and 22.70 ± 3.87 to 26.91 ± 4.85 respectively. In addition, the mean PCV of the groups 1, 2 and 3 ranged between 29.7 to 39.1, 34.0 to 36.1 and 30.0 to 36.4 respectively. RBC count recorded for the treated groups, 1, 2 and 3 ranged between 29.7x10⁶/mm³ to 39.1 x10⁶ /mm3 4.4 x10⁶/mm³ to 4.5 x10⁶/mm³ and 4.2 x10⁶ /mm3 to 4.1x10⁶/mm³ respectively. The results indicated that the cocktail has the capacity to boost the PCV and RBC but should not be used for so long.