Update on the use of misoprostol in current obstetric practice

Abstract

Misoprostol is one of the most important drugs in obstetric practice today. However, because of its uterotonic effects and consequent adverse effects on the pregnant uterus and foetus, the use of this drug requires extreme caution and very close monitoring particularly in developing countries. The aim of this update is to review the pharmacokinetics and the physiology of misoprostol and to familiarise fellow practitioners with information and evidence concerning this medication as it is currently available for use in obstetric practice.

Clinics in Mother and Child Health Vol. 3(1) 2006: 483-488