Assessment of some biochemical parameters in chronic kidney disease (CKD) patients attending Usmanu Danfodiyo University Teaching Hospital, Sokoto

Abstract

In chronic kidney disease (CKD), inadequate and poor nutrition are important factors affecting the outcome and recovery from disease and injury. This study was designed to assess some nutritional indices of patients with CKD attending UDUTH Sokoto. Seventy-five CKD patients and twenty-five controls were recruited, parameters such as serum albumin, total protein, haemoglobin, vitamin D, zinc and copper were determined using standard methods. A significant (P<0.05) increase in Urea, Creatinine, Uric acid, phosphate, copper and potassium was observed in the patients as compared to the controls. There was a significant (P< 0.05) decrease in sodium, chloride, calcium, bicarbonate and albumin of the patients when compared to the control. However, there was no significant difference (p>0.05) observed in the total protein levels of the patients and the control. Therefore, these assessed parameters plays important role for the screening of malnutrition in CKD patents and if this is established, nutritional intervention can be made to these patients to minimize or prevent the advances of malnutrition problems in the CKD patients.