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Nasomucociliary Clearance Time among Healthy Nigerians


Olushola A Afolabi
Stephen B Shaibu
Segun Segun-Busari
Habeeb K, Omokanye
Lanre J Olosunde
O Monday Ajodoh
Bolorunduro F Ehalaiye

Abstract

Background: Mucociliary clearance is an important defence mechanism in the human respiratory system.
Objective: To determine reference values for Nasal Time (NMCT) among healthy Nigerian population using the saccharine test.
Methods: This was a prospective, cross-sectional, descriptive study that was carried in a Nigerian tertiary hospital using consented healthy relative of patients, hospital staffs, students and civil servants as participants after ethical approval from the institution. Using questionnaire, Information retrieved included socio-demographic profile and saccharine transit time. All information were entered into SPSS version 20.0 and analysed.
Results: one hundred and eighty eight (188) of the 200 volunteers screened satisfy the inclusion. Eighty five (85) male and 103 females, M: F of 1: 1.2. Age range was 10-85years, modal age group was 18-40years, mean age was 31.01years. Minimum NMCT recorded was 6 minutes and maximum was 43minutes with Mean NMCT 15.5minutes.
Conclusion: NMCT among healthy Nigerians was in the range of Mucociliary clearance is an important defence mechanism in the human respiratory system. Mucociliary Clearance 12.5 minutes-18.5 minutes with a mean duration of 15.5 minutes, slightly higher in females than the males and NMCT increases with age.


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eISSN: 2437-1734
print ISSN: 0189-9422