Prevalence of Entamoeba histolytica among patients with gastroenteritis attending some selected hospitals in Zaria Metropolis, Kaduna State

Abstract

Background: Amoebiasis is a cosmopolitan infection caused by Entamoeba histolytica and ranks third among parasitic infections that lead to death especially in children. Clinical features of amoebiasis range from asymptomatic colonization of amoebic colitis (dysentery or diarrhoea) and invasive extra intestinal amoebiasis, which is manifested most commonly in the form of liver abscesses.

Aim: The prevalence of E. histolytica infection in patients having gastroenteritis attending three selected hospitals in Zaria, Kaduna state was studied using direct wet mount and formol-ether concentration method. The hospitals were Hajiya Gambo Sawaba General Hospital Kofan Gayan (Gambo Sawaba), Major Ibrahim B. Abdullahi Memorial Hospital Sabon Gari, Zaria (Limi hospital) and University Health Services ABU Zaria (Sick Bay).

Methods: One hundred and forty stool samples from gastroenteritis patients of all ages attending the selected hospitals were examined for E. histolytica trophozoites/cysts via direct wet mount and formol-ether concentration method.

Results: Eight samples were positive giving an overall prevalence of 5.71%. Highest prevalence (10.4%) was obtained from patients attending Gambo Sawaba Hospital. The prevalence of 2.4% and 4.0% were recorded among gastroenteritis patients attending Limi Hospital and University (A.B.U, Zaria) health service respectively. With respect to age, the prevalence (11.4%) was highest in the age group 11-15 (years) followed by 6-10 years with prevalence of 6.38%. However, none of the socio-demographic factors examined showed significant statistical association (P>0.05).