Autism, surge in the prevalence and linkage with childhood vaccination - A Review

Abstract

Autism a neurodegenerative disorder characterised by an abnormal child behaviour like
isolation, learning difficulties, general abnormality in communication and social reciprocity, inability to maintain eye contact or point at something, looking at thing with the peripheral vision and many other neurological disorders, the aetiology of autism is multifactorial including among other social, environmental, genetics, epigenetics and
neurological factors, in recent years vaccines have drawn large interest of scientific community for its asserted role in the development of autism, this is largely due to the presence in higher concentration of a mercury containing compound thimerosal in many vaccines, and due to some evidence which link some vaccines including measles, mumps and rubella vaccines with autism, moreover several authentic scientific studies were
undertaken to falsified those findings. Here we critically review those assertion, examined some implicating component of vaccine and relate them with neurobiology of autism.