Evaluation of serum lipid profile among hyperthyroid patients in Aminu Kano Teaching Hospital, Kano

Abstract

Background: Hyperthyroidism is the condition that reflects excessive concentrations of thyroid hormones in the body that is the thyroid gland is overactive. Hyperthyroidism is thus a cause of thyrotoxicosis, the clinical condition of increased thyroid hormone in the blood (Cleve 2009).
Aim: The aim of this study was to evaluate serum lipid profile among hyperthyroid patients in Aminu Kano Teaching Hospital
Methodology: A total of 62 subjects were used for this study 31 hyperthyroid patients and 31 Control subjects. The blood samples were centrifuged, serum collected and analyzed  spectrophotometrically using enzymatic reaction for {total cholesterol, triglycerides and HDL] while LDL was determined by freidwalds formula.
Results: The results show that serum TC, HDL-C, LDLC-C and TG levels were significantly lower in patients than in controls. There were negative and significant correlation between T3 and TC, T3 and TG, TSH and TG in patients (r=~0.292 p<0.05, r=-0.529 p<0.001 and r-0.487 p<0.001 respectively), while there was positive and significant correlation between serum T4 and LDL-C in controls (r=0.426, p<0.05).
Conclusion: It can be concluded that serum lipids were significantly reduced in hyperthyroid patients.