Effect of Hibiscus sabdariffa calyx extract on carbon tetrachloride induced liver damage

Abstract

The effect of aqueous ethanol (1:1) extract of the calyx of Hibiscus sabdariffa on carbon tetrachloride (CCl₄) induced liver damage was investigated. Oral administration of the extract following a single CCl₄ dose promoted the healing of oxidative liver damage as determined by serum aminotransferases, ALT, AST, levels and liver thiobarbituric acid reactive substances levels. It appeared from the study that the extract of Hibiscus sabdariffa enhances the recovery from hepatic damage induced by CCl₄.

Key words: Carbon tetrachloride, Hibiscus sabdariffa, Liver damage.