Effect of palm oil and beef liver on diesel-induced haematotoxicity in wistar albino rats

Abstract

The purpose of this study was to investigate the effects of palm oil and beef liver on some haematological parameters of rats fed with diesel-contaminated diets. Thirty wistar albino rats were equally divided into six groups with group1 as the control. Rats in groups 2, 3, 4, 5 and 6 were fed with diesel-contaminated diets only, diesel-contaminated diets plus palm oil and diesel-contaminated diets plus beef liver, respectively. The result of the experiment showed a significant decrease (P<0.05) in haemoglobin (Hb), Red blood cell (RBC), packed cell volume (PCV), mean cell volume (MCV), and mean cell haemoglobin (MCH) in rats fed with diesel- contaminated diet compared with the controls, the palm oil and the beef liver groups. However, there was a significant increase in white blood cell (WBC) count and lymphocytes in rats fed diesel-contaminated diet and the beef liver group relative to the control and the palm oil groups. This study suggests that palm oil and beef liver may confer some protective roles against haematotoxicity caused by diesel.

Keywords: Contaminated-diet, diesel, haematotoxicity.