Main Article Content
Synthesis, characterization and antibacterial activity of 2-p-tolyl-1H-imidazo[4,5-f][1,10] phenanthroline and its Co(II), Ni(II) and Cu(II) complexes
Abstract
In this study, the ligand, 2-p-tolyl-1H-imidazo[4,5-f][1,10]phenanthroline (L) was synthesized by the reaction of 1,10-phenanthroline-5,6-dione with 4-methylbenzaldehyde. The complexes of L were prepared with Co(II), Ni(II) and Cu(II) chlorides. The ligand and its complexes were characterized by IR, UV/VIS, 1H NMR, TGA, elemental analyses, molar conductivity and magnetic susceptibility. The complexes were proposed to be distorted octahedral geometry. Antibacterial activity of the ligand and its complexes were tested against selected bacteria. The minimum inhibitory concentration (MIC) was determined for the ligand and its complexes.
KEY WORDS: 1,10-Phenanthroline, Imidazole, Cobalt complex, Nickel complex, Copper complex, Antibacterial activity
Bull. Chem. Soc. Ethiop. 2013, 27(2), 213-220.