Synthesis of 1-amidoalkyl-2-naphthols based on a three-component reaction catalyzed by boric acid as a solid heterogeneous catalyst under solvent-free conditions

Abstract

An efficient method for the preparation of 1-amidoalkyl-2-naphthols has been described using a multi-component, one-pot condensation reaction of 2-naphthol, aldehydes and amides in the presence of boric acid under solvent-free conditions.

KEY WORDS: 1-Amidoalkyl-2-naphthols, Boric acid, 2-Naphthol, Solvent-free synthesis

Bull. Chem. Soc. Ethiop. 2012, 26(3), 473-478.

DOI: http://dx.doi.org/10.4314/bcse.v26i3.18