Synthesis and bioactivity of rotenone oxime O-ether derivatives

Abstract

A series of rotenone oxime O-ether derivatives were synthesized and characterized. All compounds were tested for their insecticidal, miticidal and fungicidal activities against the selected pests and compared with those of rotenone. The results of biological tests show that the rotenone oxime O-ether derivatives have improved insecticidal but weak miticidal activities against M. eparate, N. cincticeps, T. urticae compared with rotenone. The disustituted oxime O-ethers showed novel fungicidal activity against R. solani with an inhibition of 80.7-95.2%.

KEY WORDS: Rotenone oxime O-ether, Synthesis, Insecticidal activity, Miticidal activity, Fungicidal activity

Bull. Chem. Soc. Ethiop. 2012, 26(3), 421-428.

DOI: http://dx.doi.org/10.4314/bcse.v26i3.11