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DABCO as a novel and efficient catalyst for the synthesis of 4(3H)-quinazolinone derivatives


Majid M. Heravi
Najme Javanmardi
Hossein A. Oskooie
Bita Baghernejad

Abstract

4(3H)-Quinazolinones were synthesized in high to excellent yields through the one-pot condensation of anthranilic acid, trimethyl orthoformate and primary amines in the presence of DABCO under solvent free conditions.

KEY WORDS: 4(3H)-Quinazolinone, DABCO (1,4-diazabicyclo[2,2,2]octane), Trimethyl orthoformate, Anthranilic acid

 

Bull. Chem. Soc. Ethiop. 2011, 25(2), 305-308.

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eISSN: 1726-801X
print ISSN: 1011-3924