Bioassay studies of metal(II) complexes of 2,2'-(ethane-1,2-diyldiimino)diacetic acid

Abstract

Ni(II), Cu(II) and Zn(II) coordination compounds with modified diammine 2,2'-(ethane-1,2-diyldiimino)diacetic acid (EDDA) were prepared and characterized. Coordination complexes of the EDDA were characterized by physical measurements including elemental analysis, IR, UV-Visible, magnetic susceptibilities and conductance measurements. The complexes were screened against four pathogenic bacteria like Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus and their concentrations for maximum inhibition zones were obtained.

 KEY WORDS: EDDA, Coordination complexes, Antibacterial studies

Bull. Chem. Soc. Ethiop. 2011, 25(2), 239-245.