Kinetics of substitution of cis-bis(malonato)diaquochromate(III) with glycine, DL-alanine and DL-phenylalanine in alkaline medium

Abstract

The kinetics of interaction among amino acids such as glycine, DL-alanine and DL-phenylalanine and cis-bis(malonato)diaquochromate(III) has been studied spectrophotometrically as a function of [glycine], [DL-alanine] and [DL-phenylalanine] in alkaline medium. The effect of pH, temperature and substrate was also studied. The substitution reaction has been found to proceed via two steps: amino acid dependent and amino acid independent path. In this process, it indicated that the substitution reaction occurs through an I_a mechanism in the amino acid dependent path and a dissociative mechanism in the independent path, showing the higher reactivity of single ended malonate complex.

KEY WORDS: Substitution, cis-bis(Malonato)diaquochromate(III), Amino acids, Alkaline medium

Bull. Chem. Soc. Ethiop. 2011, 25(1), 103-110.