Estimations of cholesterol, triglycerides and fractionation of lipoproteins in serum samples of some Nigerian female subjects

Abstract

Blood samples (serum) were collected to determine some biochemical parameters: total glycerides (TG), total cholesterol (TC), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C) and very low density lipoprotein-cholesterol (VLDL-C) in 53 female subjects in Warri, Delta State, Nigeria using the Reflotron® (an auto analyser), supported with the use of questionnaire to get information on age and sex. Age range of the subjects was 18–80 years. The TG levels in all the subjects were < 200 mg/dL; only one subject (1.89%) had TC < 200 mg/dL; nine subjects (17.0%) had HDL-C ≤ 35 mg/dL; for LDL-C only one subject (1.89%) had a desirable level of < 130 mg/dL; for VLDL-C 29 subjects (54.7%) had values 17.2 mg/dL and above. For therapeutic decision-making, TC/HDL-C and LDL-C/HDL-C, were calculated. In TC/HDL-C, three subjects (5.66%) had values < 4.4 and in LDL-C/HDL-C, 41 subjects (77.4%) had values < 4.5. Hence, TC, HDL-C, LDL-C, TC/HDL-C and slightly LDL-C/HDL-C and VLDL-C in the subjects could lead to increase coronary heart diseases. Results were matched for the age and sex of subjects.

KEY WORDS: Female serum, Biochemical studies, Therapeutic decision-making

Bull. Chem. Soc. Ethiop. 2011, 25(1), 1-10.