Studies on transition metal complexes of herbicidal compounds. II: Transition metal complexes of derivatized 2-chloro-4-ethylamino-6-isopropylamino-s-triazine (atrazine)

Abstract

2(2-Hydroxyethyl)hydrazino-4-ethylamino-6-isopropylamino-s-triazine (HEATZ), a derivative of 2-chloro-4-ethylamino-6-isopropylamino-s-triazine, atrazine (ATZ) – a well known herbicide has been studied for complex formation with cobalt(II), nickel(II), and copper(II). Analytical, conductance, thermal, and spectral studies suggest that HEATZ is a monobasic NNO donor and it forms binuclear octahedral metal complexes, possessing alkoxide bridging. Cobalt(II) complex exhibits thermochromism. Antimicrobial studies on E. coli and S. aureus show the absence of growth inhibitory activities for HEATZ and its metal complexes which is attributed to the combined effect of derivatization of ATZ and metal complexation.

KEY WORDS: Metal complexes, Atrazine derivatives, Hydrazinoethanol substitution, Monobasic tridentate NNO donor, Diminished (reduced or minimized) antimicrobial activities

Bull. Chem. Soc. Ethiop. 2003, 17(1), 35-43.