An enzyme-free electrochemical glucose sensor based on ordered porous Co3O4 material

Abstract

In this paper, Co₃O₄ was synthesized through a one-step conversion from the precursor of Co-MOF, which was prepared using the liquid phase method. It was subsequently employed to construct a novel electrochemical sensor for glucose detection. The ordered pores in the material not only provided numerous electrocatalytic active sites but also facilitated the diffusion and desorption of electrolyte ions, glucose molecules, and intermediate products, thereby enhancing the overall electrocatalytic activity.  Co₃O₄ demonstrated favorable electrocatalytic performance towards glucose oxidation. The fabricated sensor exhibited a sensitivity of 617.4 μA/(mmol·cm²), with a detection limit as low as 0.23 μmol/L and a rapid response time within 5.9 seconds over a linear range from 0.62 μmol/L to 7.5 mmol/L. The sensor possesses several advantages including straightforward fabrication, satisfactory selectivity, and a low detection limit, thus broadening the application of metal-organic frameworks in the field of electrochemical sensing.

KEY WORDS: Ordered porous material, Co₃O₄, Electrochemical sensor, Non-enzymatic glucose sensors

Bull. Chem. Soc. Ethiop. 2025, 39(5), 807-815.                                                         

DOI: https://dx.doi.org/10.4314/bcse.v39i5.1