Synthesis of some metal ion complexes of new imidazole derivative, characterization, and biological activity

Abstract

Imidazole complexes with high biological activity for some metal complexes prepared by a new imidazole ligand from the reaction of a 1,3-oxazole derivative with hydroxylamine and utilizing this ligand in the preparation of some metal ion complexes. Many of the techniques available for all prepared compounds, such as elemental analysis (CHNS), (FT-IR), (UV-Vis) spectra, and ¹H-NMR spectra, will be used in the diagnosis of these complexes, and the forms  of the complexes will be deduced from the results obtained. The outcomes demonstrated that the octahedral geometries of all the produced complexes, except for the copper and palladium complexes, which were square planer shapes. The antimicrobial activity of both the ligand and its metal ionic complexes against various microbes was evaluated.

KEY WORDS: Imidazole, Oxazole, Spectral data, Bioactivity

Bull. Chem. Soc. Ethiop. 2024, 38(6), 1681-1690.                                                           

DOI: https://dx.doi.org/10.4314/bcse.v38i6.14