Synthesis and characterization of silver nanoparticles from Cocos nucifera L. male flowers: An investigation into their potent antibacterial and anticancer efficacy

Abstract

The current research focused on the production of silver nanoparticles using dichloro methane-mediated Cocos nucifera male flower extract and their minimum inhibitory concentration against ten different bacterial pathogens. C. nucifera male flowers were extracted by 100% DCM, and the phytochemicals present in this extract were studied. These plant phytochemicals act as reducing agents to reduce the silver nitrate (AgNO₃) to silver nanoparticles (AgNPs) which was confirmed by UV/Vis spectrophotometer, Fourier transform infra-red spectrum, X-ray diffraction analysis, and scanning electron microscopy. The 15 µL of silver nanoparticles was the minimum inhibitory concentration for Klebsiella pneumonia and Bacillus subtilis. The 20 µL of silver nanoparticles is the MIC for Pseudomonas aeruginosa, Vibrio harveyi, and Plesiomonas shigelloides. 30 µL of plant flower extract concentration highly inhibits the E. coli, Staphylococcus aureus, Salmonella paratyphi, Vibrio mimicus, and Vibrio alginolyticus bacterial pathogens. C. nucifera male flowers extract derived silver nanoparticles are highly stable and have high potential activity against MCF-7 Cell line.

KEY WORDS: Cocos nucifera, Nanoparticles, Phytochemicals, Antimicrobials, Bacterial pathogens, MCF 7 Cell line

Bull. Chem. Soc. Ethiop. 2024, 38(3), 715-724.                                                            

DOI: https://dx.doi.org/10.4314/bcse.v38i3.13