Bulletin of the Chemical Society of Ethiopia
Journal / Bulletin of the Chemical Society of Ethiopia / Vol. 21 No. 3 (2007) / Articles
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Published:
Nov 26, 2007
DOI:
10.4314/bcse.v21i3.21218
Keywords:
<i>Erythrina sigmoidea</i> Stem bark Triterpenoid Saponin Isoflavone Leguminoseae

Article Details

Issue
Vol. 21 No. 3 (2007)
Section
Articles

Main Article Content

SIGMOISIDE E: A NEW ANTIBACTERIAL TRITERPENOID SAPONIN FROM ERYTHRINA SIGMOIDEA (HUA)


J. Kouam
X. Siewe Noundou
Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P. O. Box 812, Cameroon
Laure B. Kouitcheu Mabeku
Microbiology Laboratory, Department of Biochemistry, Faculty of Science, P. O. Box 812, University of Yaoundé I, Cameroon
A. Meli Lannang
Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P. O. Box 812, Cameroon
M. Iqbal Choudhary
H.E.J. Research Institute of Chemistry, International Centre of Chemical Sciences, University of Karachi-75270, Pakistan
Z.T. Fomum
Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P. O. Box 812, Cameroon

Abstract

Chemical analysis of the stem bark of Erythrina sigmoidea (Leguminoseae) yielded two known isoflavones, 6,8-diprenylgenisteine (3) and warangalone (4) as well as a new triterpenoid saponin designated sigmoiside E (1). Its structure was established by chemical and spectroscopic means as 16-O-β-D-galactopyranosyl maniladiol (1). Sigmoiside E exhibited antibacterial activity against gram-negative bacteria.

KEY WORDS: Erythrina sigmoidea, Stem bark, Triterpenoid, Saponin, Isoflavone, Leguminoseae


Bull. Chem. Soc. Ethiop. 2007, 21(3), 373-378.

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924
 
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