ANTIPARASITIC PRENYLATED ISOFLAVONOIDS FROM SEEDS OF MILLETTIA GRIFFONIANA

Abstract

Two new prenylated isoflavonoids, namely 7-methoxyebenosin and griffonianone E along with the known calopogonium isoflavone B and 7,2\'-dimethoxy-4\',5\'-methylenedioxy isoflavone were isolated from the seeds of Millettia griffoniana. Their structures were assigned on the basis of spectroscopic data. The new compounds exhibit moderate trypanocidal and anti-plasmodial activities.



KEY WORDS: Millettia griffoniana, Fabaceae, Papilionoideae, Isoflavones, Trypanocidal, Anti-plasmodial


Bull. Chem. Soc. Ethiop. 2005, 19(1), 75-80.