A facile synthesis of 1-aryl pyrroles by Clauson-Kaas reaction using oxone as a Catalyst under microwave irradiation

Abstract

A new and efficient methodology to synthesize N-substituted pyrrole derivatives by Clauson Kaas reaction employing Oxone as catalyst was developed. The transformation was performed in acetonitrile under microwave irradiation. This procedure has several advantages such as high yield, clean product formation, and short reaction time.

KEY WORDS: Synthesis, Pyrrole, Oxone, Microwave irradiation

Bull. Chem. Soc. Ethiop. 2019, 33(1), 143-148

DOI: https://dx.doi.org/10.4314/bcse.v33i1.14