Synthesis of new nano Schiff base complexes: X-ray crystallography, thermal, electrochemical and anticancer studies of nano uranyl Schiff base complexes

Abstract

This study presents synthesis and characterization of new nano uranyl Schiff base complexes. Electrochemistry of these complexes showed a quasireversible redox reaction without any successive reactions. Furthermore, X-ray crystallography exhibited that beside the coordination of tetradentate Schiff base, one solvent molecule (dimethylformamide) was also coordinated. According to Coats-Redfern plots the kinetics of thermal decomposition of the studied complexes was first-order in all stages. Anticancer activities of the uranyl Schiff base complexes against cancer cell lines (Jurkat) was studied and determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazoliumbromide) assay. The results demonstrated that the complexes with aliphatic bridging units showed less anticancer activities than those having the aromatic units.

KEY WORDS: Uranyl Schiff base complex, Anticancer activities, Thermal studies, Electrochemistry; X-ray crystallography

Bull. Chem. Soc. Ethiop. 2018, 32(1), 89-100

DOI: https://dx.doi.org/10.4314/bcse.v32i1.8