Main Article Content
Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES
Abstract
The reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates was trapped by N-formyl urea to produce highly functionalized dihydropyrimidinones in fairly good yields.
KEY WORDS: Alkyl isocyanides, Dialkyl acetylenedicarboxylate, N-Formyl urea, Three-component reaction, Dihydropyrimidinones
Bull. Chem. Soc. Ethiop. 2017, 31(2), 345-350.