Synthesis, characterization and bioactivity ¬¬¬¬Zn2+, Cu2+, Ni2+, Co2+, Mn2+, Fe3+, Ru3+, VO2+ and UO22+ complexes of 2-hydroxy-5-((4-nitrophenyl)diazenyl)benzylidene)-2-(p-tolyl- amino)acetohydrazide

Abstract

Novel azo-acetohydrazide complexes of Zn²⁺, Cu²⁺, Ni²⁺, Co²⁺, Mn²⁺, Fe³⁺, Ru³⁺, VO²⁺ and UO₂²⁺ with 2-hydroxy-5-((4-nitrophenyl)diazenyl)benzylidene)-2-(p-tolylamino)acetohydrazide have been prepared. All the compounds were analytically and spectroscopically characterized by various techniques. The data of molar conductance indicated the prepared complexes are nonelectrolyte in nature except complexes (10) and (11). The spectroscopic data point out that the behavior of ligand towards metal ions are neutral or monobasic bidentate, and dibasic tridentate ligand linked to the metal ions through oxygen atom of ketonic or enolic carbonyl group, azomethine nitrogen atom and/or deprotonated phenolic group forming either octahedral or tetragonally distorted octahedral geometry. X-ray powder diffraction analysis of complexes (2) and (3) indicate that the complexes are crystalline in nature and have monoclinic structures. The microbicides activities of all compounds evaluated by well diffusion method versus Escherichia coli and Aspergillus niger at different concentration. The bioactivities data elucidated that as the concentration of the tested solutions increases the activities increase.

KEY WORDS: Azo-acetohydrazide, Azo-hydrazone, Metal complexes, Bioactivity, X-ray diffraction analysis

Bull. Chem. Soc. Ethiop. 2017, 31(1), 75-91.

DOI: http://dx.doi.org/10.4314/bcse.v31i1.7