Nano-TiO2 as a novel and efficient catalyst for the synthesis of pyridine dicarbonitriles

Abstract

Pyridine dicarbonitriles have been synthesized in good yields via a one-pot multi–component reaction of aldehyde, malononitrile, and thiol in the presence of nano-TiO₂ as a catalyst in ethanol.

KEY WORDS: Pyridine dicarbonitriles, Multi–component reaction, One-pot, Nano-TiO₂

Bull. Chem. Soc. Ethiop. 2014, 28(1), 149-153.

DOI: http://dx.doi.org/10.4314/bcse.v28i1.18