Synthesis, Antibacterial and Antifungal Investigations of Mn (Ii) Complexes with Schiff Bases Derived From 2 – Hydroxy – 1 – Naphthaldehyde and Some Aliphatic Diamines

Abstract

Schiff base ligands derived from 2-hydroxy-1-naphthaldehyde and some aliphatic diamines were synthesized and characterized. Each of the ligands was used to form complex with Mn (II). Solubility, elemental analyses and IR spectra were carried evaluated. Elemental analyses of the complexes for C, N and H revealed 1:1 metal to ligand ratio. Antibacterial and antifungal activities were determined. Disc diffusion method was employed for these antimicrobial assays against four pathogenic bacteria (Escherichia coli, Salmonella typhi, Proteus sp. and Klebsiella pneumonae) and two fungi (Mucor sp. and Rhizopus sp.). It was found that the ligands and the complexes showed different activities against the isolates. The complexes showed higher activity than the free ligands.

Keywords: Schiff base, diamine, ligand, complex, isolates, analysis