Structural elucidation, thermal studies and antimicrobial screening of mixed ligans complexes of 4-benzylimino-2,3-dimethyl-1-phenylpyrazal-5-one and L-Lysine

Abstract

The mixed ligand complexes involving Fe(II), Co(II) and Ni(II) ions, Schiff base 4 phenylpyrazal-5-one (L₁) and L-lysine (Lys) were synthesized. The complexes were characterized on the basis of their elemental analysis, conductivity measurements, FT-IR, MS,1H-NMR and 13C-NMR spectral studies. All the synthesized complexes were subjected to simultaneous thermogravimetric analysis to study their decomposition mechanism and thermal stability. The mixed ligand complexes were screened against some strains of bacteria and fungi to study their antimicrobial activity. The complexes were found to be non-electrolytes and possessed octahedral geometry. The results showed that the metal complexes possessed better antimicrobial activity than the free ligands.