Potency of Septol® against Escherichia Coli and Staphylococcus Aureus Associated Nosocomial Infections in Specialist Hospital Gombe

Abstract

The antimicrobial properties of various dilutions of Septol® against some test and control nosocomial E. coli and  Staphylococcus aureus were investigated. Results showed that loss of viability was faster in sterile deionised water (SDW), followed by sterile tap water (STW) and then 10% sheep serum. A higher percentage of the resistant strains (S2 and E2) survived compared to the susceptible strains (S1 and E1). The viability of the cells in the disinfectant was also concentration dependent. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) values from the different diluents used were highest for serum, followed by STW, while lowest values were obtained from SDW. This study showed that the organisms exhibited some stable resistance to the disinfectants used; there is therefore a need for review of the dilutions being used. Greater concentration of the disinfectants should be used.

Key wards: Septol®, Disinfection, Susceptibility, bactericidal, viability, Decimal reduction time.