Schizophrenia and Parkinson’s disease: Selected therapeutic advances beyond the dopaminergic etiologies

Abstract

Both Schizophrenia and Parkinson’s disease are very much linked to the dopaminergic system, yet a larger understanding that goes behind this ‘‘simplified explanation’’ of the linked phenomena remains important to further novel advances. The description of factors related to both disorders including implicated receptors, the involved neurotransmitters and enzymes, pharmakons’ properties and the related symptoms and dysfunctions might have diverse consequences, mainly, the new therapeutic implications which lie on the pharmacological applications via the pathogenesis explanations and the identification of new possible targets, in addition to the potential development of new researches’ methods.

Keywords: G protein coupled receptors; Schizophrenia; Parkinson’s disease; Potential target