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MMP-9 In Follicular Fluid In PCO & Non PCO Females Undergoing ICSI
Abstract
Background: Matrix Metalloproteinase-9 (MMP-9) is a proteolytic enzyme, the significance of which in the follicle maturation has been widely studied in non-stimulated animal models and humans.
Aim: To compare the level of this enzyme in follicular fluid in PCO (polycystic ovary) and non PCO females undergoing intracytoplasmic sperm injection (ICSI).
Methods: MMP-9 was measured in the follicular fluid in 20 PCO and 30 non PCO females undergoing ICSI.
Results: Total MMP-9 showed no statistically significant difference between the two groups (p= 0.145).While, MMP-9 per oocyte showed a statistically significant difference between the two groups, (p =< 0.001). So MMP-9 per oocyte is greater in non PCO group.
Conclusions: There is no difference between MMP-9 secretion in follicular fluid in PCO and non PCO females undergoing ICSI.
Aim: To compare the level of this enzyme in follicular fluid in PCO (polycystic ovary) and non PCO females undergoing intracytoplasmic sperm injection (ICSI).
Methods: MMP-9 was measured in the follicular fluid in 20 PCO and 30 non PCO females undergoing ICSI.
Results: Total MMP-9 showed no statistically significant difference between the two groups (p= 0.145).While, MMP-9 per oocyte showed a statistically significant difference between the two groups, (p =< 0.001). So MMP-9 per oocyte is greater in non PCO group.
Conclusions: There is no difference between MMP-9 secretion in follicular fluid in PCO and non PCO females undergoing ICSI.
