Histiocytic Sarcoma: An Unusual Presentation of a Rare Entity

Abstract

Histiocytic sarcoma (HS) is a rare non-Langerhans histiocytic disorder accounting for less than 1% of all hematolymphoid disorders, with an aggressive clinical course with limited treatment options. It has a male predominance with extranodal sites as the commonest site of involvement although it can affect nodal sites, can also arise de novo from these sites or certain hematolymphoid disorders such as B-cell lymphomas, chronic lymphocytic leukemia/small lymphocytic lymphoma.