Fungal Osteomyelitis with Avascular Necrosis of Femoral Head in a Known Sickle Cell Anaemia Patient

Abstract

Fungal infection at the same site of an avascular necrosis (AVN) in sickle cell anaemia (SCA) is a rarity even though the incidence of deep fungal infection in recent time has been steadily increasing in immune-compromised, chronically ill and debilitated persons. The prevalence of AVN in SCA is approximately 10% while the burden of sickle cell disease in sub-Saharan Africa is highest globally. We present a 17year old SCA female with an AVN of right femur head and a concurrent African histoplasmosis.