Clinicoepidemiological Profile and Morphological Spectrum of Intracranial Tumors Seen in a Tertiary Health-Care Facility: A 6-year Retrospective Study

Abstract

Introduction: Brain tumors are a diverse group of primary central nervous system (CNS) tumors and each tumor has a distinctive biology, treatment, and prognosis.   The increase in the number of neurosurgeons and availability of newer diagnostic imaging techniques in our center, prompted this study, which was aimed at identifying the epidemiological pattern and the morphological spectrum of all intracranial tumors in this center and compare our findings with previous results from this institution and other centers. Materials and Methods: A retrospective study of cases of all intracranial tumors was conducted from January 2013 to December 2018. All slides were then reviewed by at least two pathologists. The age, sex, diagnosis using the World Health Organization grading, and the histological subtypes were recorded and then analyzed using the SPSS. Results: Altogether 113 intracranial tumors were identified out of 13,651 samples reported over a 6‑year period representing 0.82% of all surgical biopsies. The mean age was 45 ± 23.6 years with ages ranging from 1 year to 85 years. Males accounted for 47.8%, whereas females represented 51.3% with a male to female ratio of 1–1.1. Intracranial tumors were most common in the 41–50 years of age group. Supratentorial tumors accounted for 75.2%. Headache, loss of vision, seizure, and paresis were the common presentations accounting for 39.8%, 31.9%, 27.4%, and 19.4%, respectively. Meningiomas were the most common tumors representing 47.8%. Grade I tumors were predominant. Conclusion: Supratentorial tumors were predominant and meningiomas accounted for the majority. Headache, loss of vision, and seizure were common presentations