Effects Of Ceftriaxone On Haematological And Biochemical Parameters Of Turkey

Abstract

Short-term effects of ceftriaxone on haematological and biochemical parameters of Nigerian local turkey poults were studied. The pre-treatment blood and serum samples were collected and the weight of animals taken before the administration of body weight for a period of 4 days. The animals were weighed daiy. The results showed that eosinophilia was significantly increased (P < 0.05) and total bilirubin deceased significantly (P < 005). Furthermore, there was significant decrease in chloride ion (P < 005) and increase in bicarbonate ion (P < 0.05). Oher indices o haematology, liver function test and electrolyte titration were normal (P < 0.05). Ceftriaxone caused eosinophilia in treated samples (2.2 +-0.45^a) as compared to pre-treated samples (1.6 +- 0.89^b). Total bilirubin in the post-administration samples (135 + 1.05a) was decreased in comparison with pre-administration samples (14.82 +- 0.72^b). Chloride ion decreased in the treatedsampes (86.6 +- 8.11^a) when compared with untreated samples (98.4 +- 2.88^b). Bicarbonate ion increased (24.8 +- 1.79^a) in the experimental samples when compared to control (24.4 +- 1.34b).Conclusively, the short term administraton of ceftriaxone may cause eosinophilia, hypobilirubinaemia, hypochloraemia and increased bcarbonate ion which may be positive response to hypochloraemia.

Keywords: Haematology, Biochemical Parameters, Ceftriaxone, Turkey

Animal Research International Vol. 3 (3) 2006 pp. 562-565