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Hypoglycaemic effect of the methanol extract of Irvingia gabonensis seeds on streptozotocin diabetic rats


Judith Laure Ngondi
Emile Joachim Djiotsa
Zephyrin Fossouo
Julius Oben

Abstract

The hypoglycaemic effect of the methanol extract of Irvingia gabonensis seeds (Irvingiaceae) was examined in streptozotocin-diabetic rats. A single oral administration of the methanol extract at doses of 150 and 250mg/kg significantly (P < 0.001) lowered the plasma glucose levels in diabetic rats two hours after treatment.

Keywords: hypoglycaemic effect, methanol extract, Irvingia gabonensis seeds, diabetic rats

African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(4) 2006: 74-77

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eISSN: 0189-6016