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Antimalarial activity of Mammea Africana
Abstract
The antimalarial activity of ethanolic stembark extract of Mammea africana was studied in vivo in mice infected with Plasmodium bergheiduring early and established infections. Mammea africana extract(30 – 90mg/kg/day) exhibited a significant (P<0.05) blood schizontocidal activity both in 4-day early infection and in established infection with a significant mean survival time comparable to that of the standard drug,chloroquine, 5mg/kg/day.The stembark extract posseses a promising antiplasmodial activity which can be exploited in malaria therapy.
African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(4) 2006:43-49
African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(4) 2006:43-49
