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Antidiabetic activity of ethanolic leaf extract of Croton zambesicus Muell.(thunder plant) in alloxan diabetic rats
Abstract
Antidiabetic activity of ethanolic leaf extract of Croton zambesicus Muell. Arg. was evaluated using alloxan-induced (150mg/kg) hyperglycaemic rats. The activity of the ethanolic leaf extract was compared with that of a reference drug Chlorpropamide. The Blood Glucose Levels were measured using glucometer. The extract produced a significant (P<0.01) reduction in BGL after a single dose of the extract and in prolonged treatment (for 7 days). The antidiabetic activity was comparable to that of the reference drug-chlorpropamide.
Keywords: Croton zambesicus, antidiabetic, alloxan
African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(2) 2006: 21-26
Keywords: Croton zambesicus, antidiabetic, alloxan
African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(2) 2006: 21-26